Alexandra Butler Publications1. Butler AE, Janson J, Bonner-Weir S, Ritzel
R, Rizza RA, Butler PC. b-cell deficit and increased apoptosis in humans
with type-2 diabetes. Diabetes 52(1): 102-110, 2003.
2. Butler AE, Janson J, Soeller WC, Butler
PC. Increased beta cell apoptosis prevents adaptive increase in beta
cell mass in mouse model of type-2 diabetes, evidence for role of islet
amyloid formation rather than direct action of amyloid. Diabetes 52:
2304-2314, 2003. 3. Butler AE, Jang J, Gurlo T, Soeller WC,
Butler PC. Diabetes due to a progressive defect in beta cell mass in
rats transgenic for human islet amyloid polypeptide (HIP Rat); a new
model for type-2 diabetes. Diabetes 53: 1509-1516, 2004. 4. Meier JJ, Bhushan A, Butler AE, Rizza RA,
Butler PC. Sustained beta cell apoptosis in patients with long-standing
type 1 diabetes: indirect evidence for islet regeneration? Diabetologia
48: 2221-2228, 2005. 5. Ritzel RA, Butler AE, Rizza RA, Veldhuis
JD, Butler PC. Relationship Between Beta Cell Mass and Fasting Blood
Glucose Concentration in Humans. Diabetes Care 29(3): 717-8, 2006. 6. Meier JJ, Butler AE, Galasso R and Butler
PC. Hyperinsulinemic Hypoglycemia after Gastric Bypass Surgery is not
accompanied by islet hyperplasia or increased beta-cell turnover. Diabetes
Care 29(7): 1554-9, 2006. 7. Meier JJ, Lin JC, Butler AE, Galasso R,
Martinez DS and Butler PC. Direct Evidence of attempted beta cell regeneration
in an 89-year-old patient with recent-onset type 1 diabetes. Diabetologia
49(8): 1838-44, 2006. 8. Meier JJ, Butler AE, Galasso R, Rizza RA
and Butler PC. Increased Islet Beta Cell Replication adjacent to Intrapancreatic
Gastrinomas in Humans. Diabetologia, In Press 2006. Reviews Selected Publications 1. Butler AE, Colby TV, Weiss L, Lombard C. Lymphoepithelioma-like
carcinoma of the lung. Am Journ Surg Path, 13:632-639, 1989. 2. Weiss LM, Movahed LA, Butler AE, Swanson SA, Frierson HF, Cooper
PH, Colby TV, Mills SE. Analysis of lymphoepithelioma and lymphoepithelioma-like
carcinomas for Epstein-Barr viral genomes by in situ hybridization.
Am Journ Surg Path 13:625-631, 1989. 3. Butler AE, Roche PC, Carter WB, Chou J, Rizza RA, Butler PC. Measurement
of amylin in pancreatic tissue and plasma in type 2 diabetes mellitus.
Diabetologia 33:188A, 1990. 4. Butler PC, Butler AE, Roche PC. Islet-associated polypeptide (IAPP)
deposits in non insulin-dependent diabetes mellitus; cause or effect?
Clin Res 39:306A, 1991. 5. O'Brien TD, Butler AE, Johnson KH, Butler PC. Intracellular islet-amyloid
polypeptide derived amyloid in human insulinomas and extreme insulin
resistance. Diabetologia 35:454A, 1992 6. O'Brien TD, Butler AE, Porksen N, Johnson K, Butler PC. Evidence
for intracellular development of islet amyloid polypeptide (IAPP) derived
amyloid in insulinoma. Clin Res 41:102A, 1992. 7. O'Brien TD, Butler AE, Porksen N, Johnson K, Butler PC. Islet amyloid
polypeptide (IAPP) derived amyloid in human insulinoma, evidence for
intracellular development. Clin Res 41:300A, 1993. 8. Chetty R, Butler AE. Lymphocytic mastopathy associated with infiltrating
lobular breast carcinoma. Journ Clin Path 46:376-377, 1993. 9. O'Brien TD, Butler AE, Roche PC, Johnson KH, Butler PC. Islet amyloid
polypeptide in human insulinomas; evidence for intracellular amyloidogenesis.
Diabetes 43:329-336, 1994. 10. Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler
PC. -cell deficit and increased apoptosis in humans with type-2 diabetes.
Diabetes 52 (1):102-110, 2003. 11. Butler AE, Janson J, Soeller WC, Butler PC. Increased beta cell
apoptosis prevents adaptive increase in beta cell mass in mouse model
of type-2 diabetes, evidence for role of islet amyloid formation rather
than direct action of amyloid. Diabetes 52:2304-2314,2003. 12. Butler AE, Jang J, Gurlo T, Soeller WC, Butler PC (2004) Diabetes
due to a progressive defect in beta cell mass in rats transgenic for
human islet amyloid polypeptide (HIP Rat); a new model for type-2 diabetes.
Diabetes 53: 1509-1516. 13. Meier JJ, Bhushan A, Butler AE, Rizza RA, Butler PC. Evidence for
Sustained Islet Turnover in Humans With Longstanding Type-1 Diabetes.
Diabetologia Nov;48(11):2221-8. 14. Ritzel RA, Butler AE, Rizza RA, Veldhuis JD, Butler PC. Relationship
Between Beta Cell Mass and Fasting Blood Glucose Concentration in Humans.
Diabetes Care 29(3):717-8, 2006. 15. Meier JJ, Butler AE, Galasso R and Butler PC. Hyperinsulinemic
Hypoglycemia after Gastric Bypass Surgery is not accompanied by islet
hyperplasia or increased beta-cell turnover. Diabetes Care; 29(7):1554-9,
2006. 16. Meier JJ, Lin JC, Butler AE, Galasso R, Martinez DS and Butler
PC. Direct Evidence of attempted beta cell regeneration in an 89-year-old
patient with recent-onset type 1 diabetes. Diabetologia;49(8):1838-44,
2006. 17. Meier JJ, Lin JC, Butler AE, Galasso R, Martinez DS and Butler
PC. Response to comment on: Meier JJ, Lin JC, Butler AE, Galasso R,
Martinez DS, Butler PC (2006). Direct evidence of attempted beta cell
regeneration in an 89-year-old patient with Recent onset type 1 diabetes.
Diabetologia 49:1838-1844. 18. Lin CY, Gurlo T, Kayed R, Butler AE, Haataja L, Glabe CG and Butler
PC. Toxic Human IAPP Oligomers are Intracellular, and Vaccination to
Induce Anti-toxic Oligomer Antibodies Does not Prevent Human IAPP Induced
Beta-Cell Apoptosis in human IAPP transgenic mice. Diabetes. 2007 May;56(5):1324-32.
Epub 2007 Mar 12. 19. Butler AE, Huang A, Rao N, Bhushan A, Hogan WJ, Rizza RA and Butler
PC. Hematopoietic stem cells derived from adult donors are not a source
of pancreatic beta-cells in adult nondiabetic humans. Diabetes. 2007
Jul;56(7):1810-6. Epub 2007 Apr 24. 20. Huang CJ, Lin CY, Haataja L, Gurlo T, Butler AE, Rizza RA, and
Butler PC. High expression rates of human islet amyloid polypeptide
induce endoplasmic reticulum stress mediated beta-cell apoptosis, a
characteristic of humans with type 2 but not type 1 diabetes. Diabetes.
2007 Aug;56(8):2016-27. Epub 2007 May 2. 21. Butler AE, Galasso R, Meier JJ, Basu R, Rizza RA and Butler PC.
Modestly increased beta cell apoptosis but no increased beta cell replication
in recent onset type 1 diabetic patients who died of diabetic ketoacidosis.
Diabetologia Nov;50(11):2323-31, 2007. 22. Saisho Y, Butler AE, Meier JJ, Monchamp T, Allen-Auerbach M, Rizza
RA and Butler PC. Pancreas Volumes in Humans from Birth to Age One Hundred
Taking Into Account Sex, Obesity, and Presence of Type-2 Diabetes. Clin
Anat Sep;18, 2007. 23. Huang CJ, Haataja L, Galasso R, Gurlo T, Butler AE, Wu X, Soeller W and Butler PC. Induction of endoplasmic reticulum stress induced beta cell apoptosis and accumulation of polyubiquinated proteins by human islet amyloid polypeptide. Am J Physiol Endocrinol Metab Oct, 2007. Reviews 1. Butler AE and Butler PC. Beta cell dysfunction and Death in Type
2 Diabetes. Internat Diab Mon 18:29-30, 2006. 2. Butler AE and Butler PC. Life and Death of Beta Cells in the Islets
of Langerhans in Type-2 Diabetes. International Diabetes Mon 18(4):1-6,
2006. 3. Butler PC, Meier JJ, Butler AE and Bhushan A. Beta cell replication
in disease and normal physiology. (In press in Nature Medicine 2007).
. |
||||
